Publications

2021

Heath-Heckman, E., Nishiguchi, M.K. 2021. Leveraging Short-Read Sequencing to Explore the Genomics of Sepiolid Squid. Integr Comp Biol. doi: 10.1093/icb/icab152.

Bennett, G.M., Heath-Heckman, E, and Sogin, E.M. 2021. Finding Needles in Haystacks and Inferring Their Function: Challenges and Successes in Beneficial Symbiosis Research. mSystems. doi: 10.1128/mSystems.00243-21.

Heath-Heckman, E.A.C., Yoo, S., Pellegrino, M., Angstadt, J., Bautista, D., Fernandez De Miguel, F., and Weisblat, D. 2021. Transcriptional Profiling of Identified Neurons in Leech. BMC Genomics. https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-021-07526-0

2020

Kuo, D-H., De-Miguel, F., Heath-Heckman, E., Szczupak, L., Todd, K., Weisblat, D., and Winchell, C. 2020. A Tale of Two Leeches: toward the Understanding of the Evolution and Development of Behavioral Neural Circuits. Evol. Dev. https://doi.org/10.1111/ede.12358.

2019

Kim, R.C., Le, D., Ma, K., Heath-Heckman, E.A.C., Whitehorn, N., Kristan, W.B., and Weisblat, D.A. 2019. Behavioral Analysis of Substrate Texture Preference in a Leech, Helobdella austinensis. J. Comp. Physiol A. 205(2):191-202

2018

Kremer, N., Koch, E., El Filali, A., Zhou, L., Heath-Heckman, E.A.C., Ruby, E., and McFall-Ngai, M. 2018. Persistent interactions with bacterial symbionts directs mature host cell morphology and gene expression in the squid-vibrio symbiosis. mSystems. 3(5).

2017

Nawroth, J.C., Guo, H., Koch, E., Heath-Heckman, E.A.C., Hermanson, J.C., Ruby, E.G., Dabiri, J.O., Kanso, E., and McFall-Ngai, M. 2017. Motile Cilia Create Fluid-Mechanical Microhabitats for the Active Recruitment of the Host Microbiome. Proc. Natl. Acad. Sci. U.S.A. 114(36): 9510-9516.

Peyer, S.M., Heath-Heckman, E.A.C., and McFall-Ngai, M.J. 2017. Characterization of the Cell Polarity Gene Crumbs During the Early Development and Maintenance of the Squid-Vibrio Light Organ Symbiosis. Dev. Genes. Evol. 227(6):375-387.

2016

Heath-Heckman, E.A.C. 2016. The Metronome of Symbiosis: Interactions Between Microbes and the Host Circadian Clock. Integr Comp Biol. 56(5): 776-783.

Heath-Heckman, E.A.C., Foster, J., Apicella, M.A., Goldman, W.E., McFall-Ngai, M. 2016. Environmental cues and Symbiont MAMPs function in concert to drive the daily remodeling of the crypt-cell brush border of the Eupryma scolopes light organ. Cell Microbiol. 18(11): 1642-1652.

2015

Schwartzman J., Koch E., Heath-Heckman E.A.C., Zhou L., Kremer N., McFall-Ngai M., and Ruby E. 2015. The chemistry of negotiation: Rhythmic, glycan-driven acidification in a symbiotic conversation. Proc. Natl. Acad. Sci. U.S.A. 112(2):566-71.

2014

Heath-Heckman, E.A.C.*, Gillette, A.A.*, Augustin, R., Gillette M.X., Apicella, M.A., Goldman, W.E., McFall-Ngai, M.J. 2014. Shaping the microenvironment: evidence for the influence of a host galaxin on symbiont acquisition and maintenance in the squid-vibrio symbiosis. Environ Microbiol. 16(12):3669-82.

Koropatnick, T., Goodson, M. S., Heath-Heckman, E.A.C., and McFall-Ngai, M. 2014. Identifying the cellular mechanisms of symbiont-induced epithelial morphogenesis in the squid-vibrio association. Biol. Bull. 226(1):56-68.

2013

Heath-Heckman, E.A.C., S.M. Peyer, C.A. Whistler, M.A. Apicella, W.E. Goldman, and M.J. McFall-Ngai. 2013. Bacterial bioluminescence regulates expression of a host cryptochrome gene in the squid-vibrio symbiosis. mBio 4(2):e00167-13.

Kremer, N.K., Philipp, E., Charpentier, M-C., Brennan, C., Kraemer, L., Altura, M.A., Augustin, R., Haesler, R., Heath-Heckman, E.A.C., et al. 2013. Initial symbiont contact orchestrates organ-wide transcriptional changes that prime tissue colonization. Cell Host Microbe 14(2): 183-194

Altura, M.A., Heath-Heckman, E.A.C., Gillette, A.A., Kremer, N., Krachler, A-M., Brennan, C., Ruby, E.G., Orth, K., and McFall-Ngai, M.J. 2013. The first engagement of partners in the Euprymna scolopes – Vibrio fischeri symbiosis is a two-step process initiated by a few environmental symbiont cells. Environ. Microbiol. 15(11): 2937-2950.

Chaston, J.M., Murfin, K.E., Heath-Heckman, E.A.C., and Goodrich-Blair, H. 2013. Previously unrecognized stages of species-specific colonization in the mutualism between Xenorhabdus bacteria and Steinernema nematodes. Cell. Microbiol. 15(9): 1545-1559.

2012

McFall-Ngai, M.J., Heath-Heckman, E.A.C., Gillette, A.A., Peyer, S.M., and Harvie, E.A. 2012. The secret languages of coevolved symbioses: insights from the Euprymna scolopes – Vibrio fischeri symbiosis. Semin. Immunol. 24(1): 3-8.

Mandel, M.J., Schaefer, A.L., Brennan, C.A., Heath-Heckman, E.A.C., Deloney-Marino, C.R., McFall-Ngai, and M.J., Ruby, E.G. 2012. Squid-derived chitin oligosaccharides are a chemotactic signal during colonization by Vibrio fischeri. Appl. Environ. Microbiol. 78(13): 4620-4626.

2011

Heath-Heckman, E.A.C., and McFall-Ngai, M.J. 2011. The occurrence of chitin in the hemocytes of invertebrates. Zoology (Jena). 114(4): 191-198.